Database/Emulsifier/Cetearyl Glucoside
100% natural origin · ISO 16128

Is Cetearyl Glucoside natural?

Yes. Alkyl glucoside from cetearyl (C16-18) alcohol and D-glucose, both natural-origin; the record's formula field appears mismatched to an unrelated compound.

INCI nameCetearyl Glucoside
CAS246159-33-1
FunctionEmulsifier · Surfactant
FeedstockCetearyl Glucoside is made by Fischer glycosidation of…

How we scored it

C16-18 fatty alcohol (natural, oleochemical) + glucose (natural) condensed with water loss; both fragments natural → 1.00. Supplied formula/IUPAC do not match a glucoside and were disregarded as erroneous.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

How it’s made

Fischer glycosidation of glucose with cetyl alcohol. Each curved arrow moves one electron pair, and the film ends on the score above.

Where it comes from

Cetearyl Glucoside is made by Fischer glycosidation of cetearyl alcohol (from palm, coconut, or tallow fatty acids) with glucose derived from corn or wheat starch. A minor petrochemical (Ziegler/oxo) route exists for C16-18 alcohols industry-wide, but cosmetic-grade cetearyl alcohol is predominantly oleochemical.

The synthesis of Cetearyl Glucoside involves the reaction between cetearyl alcohol and glucose. This process is a form of glycosylation, where a sugar moiety (glucose) is attached to an alcohol (cetearyl alcohol).

Industrially, this is often achieved through a Fischer glycosylation or a related acid-catalyzed reaction. In this process, cetearyl alcohol and glucose are reacted in the presence of an acid catalyst, such as sulfuric acid or p-toluenesulfonic acid, under controlled temperature conditions, typically ranging from 80°C to 120°C. Water is removed during the reaction to drive the equilibrium towards product formation.

Alternatively, enzymatic methods using glycosyltransferases can be employed, offering milder reaction conditions and potentially higher selectivity. However, acid-catalyzed chemical synthesis remains a dominant route for large-scale commercial production due to cost-effectiveness and established infrastructure.

Following the reaction, the crude product undergoes purification steps. These typically include neutralization of the catalyst, removal of unreacted starting materials (excess glucose and cetearyl alcohol) through washing or extraction, and potentially decolorization using activated carbon. The final product is usually obtained as a white to off-white solid or paste.

In plain English

Cetearyl Glucoside is a gentle emulsifier that helps to blend oil and water in cosmetic products, creating smooth lotions and creams. It's made by combining two ingredients derived from natural sources: glucose, which comes from plant starches like corn, and cetearyl alcohol, a fatty alcohol typically sourced from coconut or palm kernel oil.

Think of it like a bridge connecting oil and water. Without emulsifiers, your face cream would separate into oil and water layers. Cetearyl Glucoside forms a stable network that keeps these ingredients mixed together, providing a pleasant texture and helping the product spread easily on your skin. It's known for its mildness and is often used in products designed for sensitive skin.

CosIng definition: D-Glucopyranose, C16-18 alkyl glycosides

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2CETEARYL GLUCOSIDE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  3. 3CETEARYL GLUCOSIDE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=CETEARYL%20GLUCOSIDE