Database/Chelating/Tetrasodium Iminodisuccinate
Mostly petroleum · ISO 16128

Is Tetrasodium Iminodisuccinate natural?

Mostly not. Iminodisuccinate backbone is built from petrochemical maleic anhydride and ammonia; only the sodium counter-ions are natural.

INCI nameTetrasodium Iminodisuccinate
CAS144538-83-0
FormulaC8H7NNa4O8 · 337.10 Da
FunctionChelating
FeedstockMade by reacting maleic anhydride (from benzene/butane oxidation)…

How we scored it

4 Na (mineral, 91.96 Da) natural; C8H7NO8 backbone from maleic anhydride + ammonia (petrochemical) 245.14 Da = 91.96/337.10 = 0.27
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Made by reacting maleic anhydride (from benzene/butane oxidation) with ammonia, then neutralizing with sodium hydroxide. No significant natural route reported.

In plain English

A chelating agent that binds trace metal ions to keep formulas stable; marketed as a biodegradable alternative to EDTA.

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Structure

2D structure of Tetrasodium Iminodisuccinate

tetrasodium;2-(1,2-dicarboxylatoethylamino)butanedioate

PubChem CID 9927753 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Tetrasodium Iminodisuccinate. PubChem CID 9927753. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3TETRASODIUM IMINODISUCCINATE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4TETRASODIUM IMINODISUCCINATE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=TETRASODIUM%20IMINODISUCCINATE