Database/Chelating/Tetrasodium Glutamate Diacetate
Mostly natural · ISO 16128

Is Tetrasodium Glutamate Diacetate natural?

Mostly. Fermentation-derived glutamic acid is carboxymethylated with petrochemical chloroacetic acid, then neutralized with mineral sodium; the amino-acid backbone dominates the mass.

INCI nameTetrasodium Glutamate Diacetate
CAS51981-21-6
FormulaC9H9NNa4O8 · 351.13 Da
FunctionChelating
FeedstockMade by reacting fermentation-derived L-glutamic acid (from corn…

How we scored it

Glutamic acid skeleton 143 Da (fermentation) + 4 Na 92 Da (mineral) = 235 Da natural; 2 chloroacetic-acid-derived arms 116 Da petrochemical; total 351 Da; 235/351 = 0.67.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Made by reacting fermentation-derived L-glutamic acid (from corn or beet sugar) with chloroacetic acid and sodium hydroxide to give the tetrasodium salt. A biodegradable EDTA alternative.

In plain English

A water softener that binds trace metal ions so cleansers foam and stay clear. Made from fermented plant sugar (glutamic acid) modified in a further chemical reaction step.

Natural alternatives with the same function

Structure

2D structure of Tetrasodium Glutamate Diacetate

tetrasodium;(2S)-2-[bis(carboxylatomethyl)amino]pentanedioate

PubChem CID 44630158 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Tetrasodium Glutamate Diacetate. PubChem CID 44630158. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3TETRASODIUM GLUTAMATE DIACETATE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4TETRASODIUM GLUTAMATE DIACETATE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=TETRASODIUM%20GLUTAMATE%20DIACETATE