Database/Denaturant/Quinine
100% natural origin · ISO 16128

Is Quinine natural?

Yes. Alkaloid extracted directly from Cinchona officinalis bark, the dominant commercial source.

INCI nameQuinine
CAS130-95-0
FormulaC20H24N2O2 · 324.4 Da
FunctionDenaturant · Hair Conditioning
FeedstockCommercial quinine is extracted and purified from Cinchona…

How we scored it

Alkaloid isolated by extraction from Cinchona bark; whole molecule natural-origin. 1.0
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Commercial quinine is extracted and purified from Cinchona bark. A total chemical synthesis exists but is not commercially used given the cost versus extraction.

In plain English

A bitter plant compound from cinchona tree bark, used in tiny amounts as a hair/scalp denaturant and bittering agent. Obtained by extracting the bark, not made synthetically.

CosIng definition: Quinine is an alkaloid from the bark of Cinchona officinalis. It conforms to the formula

Structure

2D structure of Quinine

(R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol

PubChem CID 3034034 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Quinine. PubChem CID 3034034. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3QUININE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4QUININE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=QUININE