Database/Denaturant/Quassin
100% natural origin · ISO 16128

Is Quassin natural?

Yes. Plant bitter principle extracted from Quassia/Picrasma wood, the standard commercial source.

INCI nameQuassin
CAS76-78-8
FormulaC22H28O6 · 388.5 Da
FunctionDenaturant
FeedstockQuassin is isolated by solvent extraction of Quassia…

How we scored it

Bitter quassinoid isolated by extraction from Quassia wood; whole molecule natural-origin. 1.0
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Quassin is isolated by solvent extraction of Quassia amara or Picrasma excelsa wood. No commercial synthetic route is used.

In plain English

An intensely bitter compound extracted from quassia tree wood, used in tiny amounts to discourage nail-biting or product ingestion. Comes straight from the plant, not made synthetically.

Structure

2D structure of Quassin

(1S,2S,6S,7S,9R,13R,17S)-4,15-dimethoxy-2,6,14,17-tetramethyl-10-oxatetracyclo[7.7.1.02,7.013,17]heptadeca-4,14-diene-3,11,16-trione

PubChem CID 65571 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Quassin. PubChem CID 65571. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3QUASSIN. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4QUASSIN. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=QUASSIN