Database/Chelating/Gluconolactone
100% natural origin · ISO 16128

Is Gluconolactone natural?

Yes. Entire carbon skeleton derives from fermentation-derived glucose oxidized to gluconic acid, which cyclizes to the lactone.

INCI nameGluconolactone
CAS90-80-2
FormulaC6H10O6 · 178.14 Da
FunctionChelating · Skin Conditioning
FeedstockProduced by glucose oxidase fermentation/oxidation of corn- or…

How we scored it

D-Glucono-1,5-lactone is the direct oxidation/lactonization product of glucose; every carbon traces to glucose. No petrochemical fragment. 100% natural mass.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

How it’s made

Acid-catalysed lactonisation of gluconic acid (glucose oxidation named). Each curved arrow moves one electron pair, and the film ends on the score above.

Where it comes from

Produced by glucose oxidase fermentation/oxidation of corn- or starch-derived glucose to gluconic acid, which spontaneously forms the lactone. No significant petrochemical route exists.

In plain English

A mild exfoliating and metal-binding ingredient made from corn sugar via fermentation. It occurs naturally in honey, fruit and wine, and helps condition skin and stabilise formulas.

CosIng definition: D-Glucono-1,5-lactone

Structure

2D structure of Gluconolactone

(3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-one

PubChem CID 7027 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Gluconolactone. PubChem CID 7027. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3GLUCONOLACTONE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4GLUCONOLACTONE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=GLUCONOLACTONE