Database/Fragrance/Gamma-Nonalactone
Route-dependent · ISO 16128

Is Gamma-Nonalactone natural?

It depends. Natural route traces every carbon to a castor-oil-derived fatty acid via yeast fermentation; synthetic route traces to petrochemical oxo-aldehyde and acrylate feedstocks.

INCI nameGamma-Nonalactone
CAS104-61-0
FormulaC9H16O2 · 156.22 Da
FunctionFragrance · Skin Conditioning
FeedstockCan be produced by yeast fermentation of castor-oil-derived…

Why the score varies

This ingredient is made commercially by more than one route, and ISO 16128 scores the feedstock actually used. Without a supplier certificate of origin the value cannot be claimed.

RouteFeedstockNOIShareNotes
Petrochemical synthesisoxo-process pentyl aldehyde + acrylate-type unit, lactonised0.00~65%
Fermentationcastor-oil-derived hydroxy fatty acid beta-oxidised by Yarrowia lipolytica yeast, lactonised1.00~35%
Ask your supplier. A batch-specific certificate of origin or bio-based carbon test (ASTM D6866) settles which route applies.

How we scored it

Natural route: Yarrowia fermentation of a castor-oil-derived hydroxy fatty acid, lactonised, retains every carbon, 1.0. Synthetic route: petrochemical oxo-aldehyde + acrylate-type unit, lactonised, 0.0. Synthetic assumed larger by volume.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Can be produced by yeast fermentation of castor-oil-derived hydroxy fatty acids, trimmed and lactonised with every carbon traceable to castor oil. Alternatively synthesised from petrochemical aldehydes via oxo-synthesis and lactonisation; the synthetic route is assumed larger-volume.

In plain English

A coconut/creamy-scented fragrance ingredient. It can be produced naturally by fermenting castor-oil-derived fatty acids, or made synthetically from petrochemical building blocks; both routes are used in the fragrance industry.

Natural alternatives with the same function

Structure

2D structure of Gamma-Nonalactone

5-pentyloxolan-2-one

PubChem CID 7710 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Gamma-Nonalactone. PubChem CID 7710. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3GAMMA-NONALACTONE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4GAMMA-NONALACTONE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=GAMMA-NONALACTONE