Database/Chelating/Disodium Etidronate
Mostly petroleum · ISO 16128

Is Disodium Etidronate natural?

Mostly not. Less sodium than the tetrasodium salt lowers the natural fraction; the phosphonate backbone remains fully synthetic.

INCI nameDisodium Etidronate
CAS7414-83-7
FormulaC2H6Na2O7P2 · 249.99 Da
FunctionChelating
FeedstockMade from acetic acid/anhydride and phosphorus trichloride to…

How we scored it

Na2 46.0 Da (mineral, natural) + etidronate core C2H6O7P2 204.0 Da (synthetic) = 249.99 Da. 46.0/249.99 = 0.18.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Made from acetic acid/anhydride and phosphorus trichloride to build the phosphonate backbone, partially neutralised with sodium hydroxide.

In plain English

Disodium etidronate binds trace metals to keep a formula stable. Its core structure comes from synthetic industrial chemistry, with a small amount of sodium added.

Natural alternatives with the same function

Structure

2D structure of Disodium Etidronate

disodium;hydroxy-[1-hydroxy-1-[hydroxy(oxido)phosphoryl]ethyl]phosphinate

PubChem CID 23894 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Disodium Etidronate. PubChem CID 23894. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3DISODIUM ETIDRONATE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4DISODIUM ETIDRONATE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=DISODIUM%20ETIDRONATE