Database/Colorant/CI 45410
Mostly petroleum · ISO 16128

Is CI 45410 natural?

Mostly not. Only the sodium counter-ions are mineral-origin; the brominated/chlorinated xanthene dye core is entirely synthetic petrochemical aromatic chemistry.

INCI nameCI 45410
CAS18472-87-2
FormulaC20H2Br4Cl4Na2O5 · 829.6 Da
FunctionColorant · Hair Dyeing
FeedstockPhloxine B is synthesised from petrochemical fluorescein-type precursors…

How we scored it

Phloxine B disodium salt C20H2Br4Cl4Na2O5 829.6 Da: Na2 46.0 Da natural (counter-ion) + halogenated xanthene core 783.6 Da petrochemical → 46.0/829.6 = 0.06.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Phloxine B is synthesised from petrochemical fluorescein-type precursors via bromination and chlorination, isolated as the disodium salt. No natural production route exists.

In plain English

A synthetic pink-red xanthene dye used to colour hair and cosmetic products. Manufactured from petrochemical aromatic chemicals through halogenation, with only trace mineral sodium in the final salt.

CosIng definition: CI 45410 is classed chemically as a xanthene colour. It conforms to the formula:

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Structure

2D structure of CI 45410

disodium;2,3,4,5-tetrachloro-6-(2,4,5,7-tetrabromo-3-oxido-6-oxoxanthen-9-yl)benzoate

PubChem CID 6097185 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2CI 45410. PubChem CID 6097185. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3CI 45410. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4CI 45410. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=CI%2045410