Database/Colorant/CI 45405
Mostly petroleum · ISO 16128

Is CI 45405 natural?

Mostly not. Only the two potassium counter-ions are mineral/natural; the brominated/chlorinated xanthene dye core is synthesised from petrochemical aromatics.

INCI nameCI 45405
CAS6441-77-6
FormulaC20H4Br4Cl2K2O5 · 793.0 Da
FunctionColorant
FeedstockCI 45405 is a synthetic halogenated xanthene (fluorescein-type)…

How we scored it

Dipotassium xanthene dye: K2 = 2x39.10=78.2 Da natural; C20H4Br4Cl2O5 core (714.7 Da) petrochemical aromatic. 78.2/793.0=0.10.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

CI 45405 is a synthetic halogenated xanthene (fluorescein-type) dye made from petrochemical phenolic/phthalic feedstocks, sold as its dipotassium salt. There is no natural production route for this dye.

In plain English

A synthetic bromo/chloro xanthene dye, sold as a potassium salt, used to colour cosmetics such as lipsticks. It is made from petrochemical aromatic building blocks, not derived from plants.

CosIng definition: CI 45405 is classed chemically as a xanthene colour. It conforms to the formula:

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Structure

2D structure of CI 45405

dipotassium;2',4',5',7'-tetrabromo-4,7-dichloro-3-oxospiro[2-benzofuran-1,9'-xanthene]-3',6'-diolate

PubChem CID 22948 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2CI 45405. PubChem CID 22948. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3CI 45405. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4CI 45405. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=CI%2045405