Database/Colorant/CI 45380
Mostly petroleum · ISO 16128

Is CI 45380 natural?

Mostly not. A synthetic brominated xanthene colorant (eosin-type); only its sodium counter-ions are mineral/natural, the brominated aromatic backbone is petrochemical.

INCI nameCI 45380
CAS17372-87-1
FormulaC20H6Br4Na2O5 · 691.9 Da
FunctionColorant
FeedstockSynthesised from petrochemical phthalic anhydride and resorcinol-type aromatics,…

How we scored it

Disodium salt of a brominated xanthene (fluorescein) dye; only the two sodium counter-ions (45.98 Da) are natural; 45.98/691.9 = 0.07, the rest is synthetic brominated aromatic dye.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Synthesised from petrochemical phthalic anhydride and resorcinol-type aromatics, then brominated and neutralised to the disodium salt. No natural production route exists for this dye.

In plain English

A synthetic pink-red colorant used to tint cosmetic products. Made from petrochemical aromatic chemicals and bromine, with only its sodium component of mineral origin.

CosIng definition: CI 45380 is classed chemically as a xanthene colour. It conforms to the formula:

Natural alternatives with the same function

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 Calcium Ferrite 100% natural origin

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 Calcium Stearate 100% natural origin

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Structure

2D structure of CI 45380

disodium;2-(2,4,5,7-tetrabromo-3-oxido-6-oxoxanthen-9-yl)benzoate

PubChem CID 11048 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2CI 45380. PubChem CID 11048. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3CI 45380. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4CI 45380. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=CI%2045380