Database/Colorant/CI 45220
Mostly petroleum · ISO 16128

Is CI 45220 natural?

Mostly not. The xanthene chromophore and ethylamino substituents are petrochemical aromatic material; the benzenedisulfonate/sodium portion is mineral-origin natural.

INCI nameCI 45220
CAS5873-16-5
FormulaC25H25N2NaO7S2 · 552.6 Da
FunctionColorant
FeedstockCI 45220 is a synthetic xanthene (rhodamine-type) dye…

How we scored it

Two sulfonate groups + Na (~183 Da, natural mineral fragment) subtracted from MW 552.6 -> 370 Da xanthene/ethylamino backbone (petrochemical) -> 183/553 = 0.33.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

CI 45220 is a synthetic xanthene (rhodamine-type) dye built from petrochemical aromatic intermediates. No natural extraction route exists for this dye class.

In plain English

A synthetic xanthene dye used to add red-pink colour to cosmetic products.

CosIng definition: CI 45220 is classed chemically as a xanthene colour. It conforms to the formula:

Natural alternatives with the same function

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Structure

2D structure of CI 45220

sodium 4-[3-(ethylamino)-6-ethylazaniumylidene-2,7-dimethylxanthen-9-yl]benzene-1,3-disulfonate

PubChem CID 65196 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2CI 45220. PubChem CID 65196. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3CI 45220. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4CI 45220. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=CI%2045220