Database/Colorant/CI 45100
Mostly petroleum · ISO 16128

Is CI 45100 natural?

Mostly not. Synthetic xanthene dye. Its two sulfonate groups and sodium counter-ion count as natural under the site's counter-ion convention; the coloured carbon skeleton is petrochemical. Same substance and value as Acid Red 52.

INCI nameCI 45100
CAS3520-42-1
FormulaC27H29N2NaO7S2 · 580.7 Da
FunctionColorant · Hair Dyeing
FeedstockPetrochemical diethylaminophenol and sulfonated benzaldehyde condensed into the…

How we scored it

CI 45100 (sulforhodamine B, the colorant listing of Acid Red 52) C27H29N2NaO7S2 580.6 Da: 2×SO3 160.1 Da + Na 23.0 Da are mineral-derived (natural) = 183.1 Da; the xanthene chromophore is petrochemical → 0.32. Matches the site's Acid Red 52 entry.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Petrochemical diethylaminophenol and sulfonated benzaldehyde condensed into the xanthene dye and isolated as the sodium salt.

In plain English

A bright pink-red synthetic dye used to colour hair and cosmetics. It is built in a lab from petroleum-derived chemicals, with only a trace of natural mineral sodium in its structure.

CosIng definition: CI 45100 is classed chemically as a xanthene colour. It conforms to the formula:

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Structure

2D structure of CI 45100

sodium 4-[3-(diethylamino)-6-diethylazaniumylidenexanthen-9-yl]benzene-1,3-disulfonate

PubChem CID 9916275 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2CI 45100. PubChem CID 9916275. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3CI 45100. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4CI 45100. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=CI%2045100