Database/Fragrance/Acetyl Hexamethyl Indan
100% petroleum · ISO 16128

Is Acetyl Hexamethyl Indan natural?

No. Built from p-cymene (toluene and propylene), isoamylene and an acetyl cap, all petrochemical.

INCI nameAcetyl Hexamethyl Indan
CAS15323-35-0
FormulaC17H24O · 244.37 Da
FunctionFragrance · Perfuming
FeedstockDominant route is cyclo-alkylation of p-cymene with isoamylene…

How we scored it

C17H24O 244.4: p-cymene fragment 131.2, isoamylene 70.1, acetyl 43.0, all petrochemical; 0/244.4 = 0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Dominant route is cyclo-alkylation of p-cymene with isoamylene followed by Friedel-Crafts acetylation, all from petrochemical sources. Cymene from sulfite turpentine is a possible but minor alternative.

In plain English

A synthetic musk fragrance ingredient (Phantolide) with a sweet, powdery, woody-musky note, used to round out and fix perfumes. It is made from petrochemical aromatics.

Natural alternatives with the same function

Structure

2D structure of Acetyl Hexamethyl Indan

1-(1,1,2,3,3,6-hexamethyl-2H-inden-5-yl)ethanone

PubChem CID 47167 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Acetyl Hexamethyl Indan. PubChem CID 47167. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3ACETYL HEXAMETHYL INDAN. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4ACETYL HEXAMETHYL INDAN. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=ACETYL%20HEXAMETHYL%20INDAN