Valine has a Natural Origin Index (NOI) of 1.00 (scale 0–1) per ISO 16128. Amino acid produced by microbial fermentation of plant sugars or by protein hydrolysis; no petrochemical fragment. An NOI of 1.00 means 100% of its molecular mass is traceable to a natural, renewable source.

Is Valine natural? NOI 1.00 — Is That Natural?

How we scored it

Valine C5H11NO2, a proteinogenic amino acid; amino acids are fermentation/hydrolysate products, fully natural-origin. 1.0.

What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Manufactured industrially by bacterial fermentation of plant-derived sugars (molasses, corn glucose); also recoverable from protein hydrolysates. Fermentation is the dominant cosmetic-grade route.

In plain English

An amino acid used to condition hair and skin and reduce stickiness in formulas. It's produced by fermenting plant sugars, the same way many food-grade amino acids are made.

Structure

(2S)-2-amino-3-methylbutanoic acid

PubChem CID 6287 ↗

References

1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
2Valine. PubChem CID 6287. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
3VALINE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
4VALINE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=VALINE