How we scored it
Nucleoside C9H12N2O6: ribose + uracil, both fermentation-derived carbohydrate/pyrimidine building blocks, no petrochemical fragment. 244.20/244.20 = 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.
Where it comes from
Uridine is manufactured industrially by microbial fermentation of glucose, the standard route for cosmetic-grade nucleosides. No petrochemical route is commercially used.
In plain English
Uridine is a building block of RNA that helps condition and protect skin. It's produced by fermenting plant sugars with microorganisms, similar to how some vitamin-like ingredients are made.
Structure
1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2Uridine. PubChem CID 6029. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
- 3URIDINE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 4URIDINE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=URIDINE