Database/Antioxidant/Ubiquinol
100% natural origin · ISO 16128

Is Ubiquinol natural?

Yes. Made by chemically reducing fermentation-derived Coenzyme Q10; no petrochemical fragment is introduced.

INCI nameUbiquinol
CAS56275-39-9
FormulaC59H92O4 · 865.4 Da
FunctionAntioxidant · Humectant
FeedstockProduced by microbial fermentation to make Coenzyme Q10,…

How we scored it

Reduced Coenzyme Q10; parent CoQ10 is a fermentation product; reduction adds only two hydrogen atoms, negligible non-natural mass.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Produced by microbial fermentation to make Coenzyme Q10, then chemically reduced to ubiquinol. No petrochemical route is used commercially.

In plain English

The active, antioxidant form of Coenzyme Q10, made by fermenting microbes and then converting the result chemically. Used in skincare for its antioxidant effect.

CosIng definition: Ubiquinones, reduced

Structure

2D structure of Ubiquinol

2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyltetraconta-2,6,10,14,18,22,26,30,34,38-decaenyl]-5,6-dimethoxy-3-methylbenzene-1,4-diol

PubChem CID 9962735 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Ubiquinol. PubChem CID 9962735. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3UBIQUINOL. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4UBIQUINOL. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=UBIQUINOL