Database/Skin Conditioning/Troxerutin
Mostly natural · ISO 16128

Is Troxerutin natural?

Mostly. Rutin extracted from plant buds is hydroxyethylated with petrochemical ethylene oxide to improve solubility.

INCI nameTroxerutin
CAS7085-55-4
FormulaC33H42O19 · 742.7 Da
FunctionSkin Conditioning
FeedstockRutin extracted from Sophora japonica (pagoda tree) flower…

How we scored it

Rutin C27H30O16 610.54 Da (natural flavonoid glycoside) + 3x hydroxyethyl C2H4O 132.15 Da (petrochemical, ethylene oxide) = 610.54/742.7 = 0.82
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Rutin extracted from Sophora japonica (pagoda tree) flower buds, then reacted with petrochemical ethylene oxide. Single dominant commercial route.

In plain English

A modified form of rutin, a plant flavonoid from pagoda tree buds, made more water-soluble for use as a skin-conditioning ingredient.

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Structure

2D structure of Troxerutin

2-[3,4-bis(2-hydroxyethoxy)phenyl]-5-hydroxy-7-(2-hydroxyethoxy)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one

PubChem CID 5486699 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Troxerutin. PubChem CID 5486699. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3TROXERUTIN. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4TROXERUTIN. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=TROXERUTIN