Database/Skin Conditioning/Tripeptide-9 Citrulline
100% natural origin · ISO 16128

Is Tripeptide-9 Citrulline natural?

Yes. Citrulline and the tripeptide's amino acids are fermentation/protein-hydrolysate products; peptide bond formation only loses water.

INCI nameTripeptide-9 Citrulline
FunctionSkin Conditioning
FeedstockMade by coupling fermentation-derived amino acids (aspartic acid,…

How we scored it

All fragments are amino acids (aspartic acid, lysine, valine) plus citrulline, joined by peptide/amide bonds; condensation water carries no petroleum mass → 1.0
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Made by coupling fermentation-derived amino acids (aspartic acid, lysine, valine) with citrulline via solid-phase peptide synthesis. No petrochemical route is commercially significant.

In plain English

A lab-made chain of amino acids joined to citrulline, used to condition skin. The amino acid building blocks come from fermentation, the same process used to make many fermented foods.

CosIng definition: Tripeptide-9 Citrulline is the reaction product of Citrulline and Tripeptide-9; Aspartic acid, synthetic tripeptide with lysine and valine, reaction product with 5-ureido-2-aminopentanoic acid

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2TRIPEPTIDE-9 CITRULLINE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  3. 3TRIPEPTIDE-9 CITRULLINE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=TRIPEPTIDE-9%20CITRULLINE