Database/Skin Conditioning/Tripeptide-6
100% natural origin · ISO 16128

Is Tripeptide-6 natural?

Yes. Assembled by peptide synthesis from natural-origin amino acids; coupling agents and solvents leave no mass in the product.

INCI nameTripeptide-6
CAS22028-82-6
FormulaC12H19N3O5 · 285.30 Da
FunctionSkin Conditioning
FeedstockManufactured by solid-phase or solution peptide synthesis from…

How we scored it

Synthetic peptide built from glycine, hydroxyproline and proline; amino acids are fermentation/hydrolysate-derived, so fully natural origin.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Manufactured by solid-phase or solution peptide synthesis from glycine, proline and hydroxyproline, which are produced by fermentation or protein hydrolysis. No petrochemical fragment remains in the final peptide.

In plain English

A lab-assembled peptide made from three natural amino acids, used to condition skin. The amino-acid building blocks come from fermentation or protein hydrolysis, not petroleum.

CosIng definition: Tripeptide-6 is a synthetic peptide consisting of glycine, hydroxyproline and proline

Structure

2D structure of Tripeptide-6

(2S)-1-[(2S,4R)-1-(2-aminoacetyl)-4-hydroxypyrrolidine-2-carbonyl]pyrrolidine-2-carboxylic acid

PubChem CID 72941529 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Tripeptide-6. PubChem CID 72941529. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3TRIPEPTIDE-6. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4TRIPEPTIDE-6. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=TRIPEPTIDE-6