How we scored it
Tripeptide of glycine-proline-hydroxyproline; amino acid building blocks are natural and condensation loses only water = 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.
Where it comes from
Synthesised by coupling fermentation- or collagen-hydrolysate-derived amino acids (Gly-Pro-Hyp), mimicking a collagen fragment. No petrochemical fragment is retained in the final peptide.
In plain English
A small lab-made peptide built from three amino acids found in collagen, used in skincare to help condition and support the look of skin.
CosIng definition: Tripeptide-29 is the synthetic peptide consisting of glycine, proline and hydroxyproline
Structure
(2S,4R)-1-[(2S)-1-(2-aminoacetyl)pyrrolidine-2-carbonyl]-4-hydroxypyrrolidine-2-carboxylic acid
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2Tripeptide-29. PubChem CID 11778669. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
- 3TRIPEPTIDE-29. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 4TRIPEPTIDE-29. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=TRIPEPTIDE-29