Database/Skin Conditioning/Tripeptide-12
100% natural origin · ISO 16128

Is Tripeptide-12 natural?

Yes. All amino-acid building blocks are natural-origin fermentation products regardless of lab coupling method.

INCI nameTripeptide-12
FunctionSkin Conditioning
FeedstockSynthesised by coupling the natural amino acids glycine,…

How we scored it

Assembled from glycine, proline and arginine (fermentation/hydrolysate amino acids); coupling reagents leave no mass.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Synthesised by coupling the natural amino acids glycine, proline and arginine. Synthesis reagents contribute no mass to the final peptide.

In plain English

A lab-assembled chain of three amino acids (glycine, proline, arginine) used in skincare to help firm and hydrate skin.

CosIng definition: Tripeptide-12 is a synthetic peptide consisting of glycine, proline and arginine; Glycine, synthetic tripeptide with proline and arginine

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2TRIPEPTIDE-12. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  3. 3TRIPEPTIDE-12. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=TRIPEPTIDE-12