How we scored it
Conjugate of citrulline + tripeptide (Asp-Ile-Lys); all amino-acid fragments are natural-origin = 1.0
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.
Where it comes from
Made by linking the amino acid citrulline to a tripeptide of aspartic acid, isoleucine and lysine, all sourced from fermentation or protein hydrolysis. No petrochemical fragment is retained.
In plain English
A lab-made combination of the amino acid citrulline and a three-amino-acid peptide, used to condition skin. The amino acid components typically come from fermentation.
CosIng definition: Tripeptide-10 Citrulline is the reaction product of Citrulline and Tripeptide-10; Aspartic acid, synthetic tripeptide with isoleucine and lysine, reaction product with 5-ureido-2-aminopentanoic acid
Structure
(3S)-4-[[(2S,3S)-1-[[(2S)-1-amino-5-(carbamoylamino)-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-[[(2S)-2,6-diaminohexanoyl]amino]-4-oxobutanoic acid
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2Tripeptide-10 Citrulline. PubChem CID 90479646. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
- 3TRIPEPTIDE-10 CITRULLINE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 4TRIPEPTIDE-10 CITRULLINE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=TRIPEPTIDE-10%20CITRULLINE