Database/Skin Conditioning/Tripeptide-1
100% natural origin · ISO 16128

Is Tripeptide-1 natural?

Yes. Assembled entirely from fermentation-derived amino acids; identical backbone to the calibrated Copper Tripeptide-1 (without the copper).

INCI nameTripeptide-1
CAS49557-75-7
FormulaC14H24N6O4 · 340.38 Da
FunctionSkin Conditioning · Skin Protecting
FeedstockManufactured by solid-phase peptide synthesis from fermentation-derived glycine,…

How we scored it

Three amino acids (glycine, histidine, lysine) joined by amide bonds; all fermentation-derived, coupling reagents leave no mass. Whole molecule = 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Manufactured by solid-phase peptide synthesis from fermentation-derived glycine, histidine and lysine. Synthesis reagents and protecting groups leave no mass in the final peptide.

In plain English

A skin-conditioning peptide made from three amino acids (glycine, histidine and lysine), the same sequence found in the body's own copper-binding peptide. It is manufactured by joining fermentation-derived amino acids together.

CosIng definition: Tripeptide-1 is a synthetic peptide containing glycine, histidine, and lysine

Structure

2D structure of Tripeptide-1

(2S)-6-amino-2-[[(2S)-2-[(2-aminoacetyl)amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoic acid

PubChem CID 73587 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Tripeptide-1. PubChem CID 73587. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3TRIPEPTIDE-1. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4TRIPEPTIDE-1. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=TRIPEPTIDE-1