Database/Skin Conditioning/Transglutaminase
100% natural origin · ISO 16128

Is Transglutaminase natural?

Yes. Microbially fermented enzyme composed entirely of natural amino-acid residues.

INCI nameTransglutaminase
CAS300711-04-0
FunctionSkin Conditioning
FeedstockCommercially produced by microbial fermentation (Streptomyces species); historically…

How we scored it

Protein enzyme; amino-acid residues are fermentation/protein-derived, natural origin. 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Commercially produced by microbial fermentation (Streptomyces species); historically also sourced from animal tissue. No petrochemical route.

In plain English

An enzyme, usually produced by fermentation, used here as a skin-conditioning ingredient.

CosIng definition: Transglutaminase is the enzyme that catalyses the formation of an amide bond between glutamine and lysine residues

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2TRANSGLUTAMINASE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  3. 3TRANSGLUTAMINASE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=TRANSGLUTAMINASE