How we scored it
Peptide-bond assembly of glutamic acid + lysine + proline x2; condensation water leaves, amino-acid mass stays. 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.
Where it comes from
Assembled from the natural amino acids glutamic acid, lysine and proline via peptide synthesis. No petrochemical fragment remains in the final peptide.
In plain English
A lab-assembled chain of four amino acids (glutamic acid, lysine and proline). Used in skincare to help condition and protect the skin.
CosIng definition: Tetrapeptide-30 is the synthetic peptide consisting of glutamic acid, lysine and proline
Structure
(2S)-6-amino-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-pyrrolidine-2-carbonyl]amino]hexanoyl]amino]-4-carboxybutanoyl]amino]hexanoic acid
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2Tetrapeptide-30. PubChem CID 25001762. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
- 3TETRAPEPTIDE-30. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 4TETRAPEPTIDE-30. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=TETRAPEPTIDE-30