Database/Hair Conditioning/Sphinganine
100% natural origin · ISO 16128

Is Sphinganine natural?

Yes. Cosmetic-grade sphinganine is produced biotechnologically by fermentation of yeast or plant sugars, the same route used for the closely related phytosphingosine.

INCI nameSphinganine
CAS764-22-7
FormulaC18H39NO2 · 301.5 Da
FunctionHair Conditioning · Skin Conditioning
FeedstockSphinganine is a sphingoid lipid naturally present in…

How we scored it

Whole sphingoid-base molecule produced by yeast or plant-sugar fermentation, analogous to phytosphingosine; all 18 carbons trace to the fermentation feedstock. 301/301 = 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Sphinganine is a sphingoid lipid naturally present in skin; the cosmetic ingredient is typically produced by fermenting yeast or plant-derived sugars rather than extracted from animal tissue. A minor chemical-synthesis route also exists.

In plain English

A lipid naturally found in skin that helps the skin barrier hold moisture. The cosmetic ingredient is typically produced by fermenting yeast or plant sugars rather than extracted from skin itself.

Structure

2D structure of Sphinganine

(2S,3R)-2-aminooctadecane-1,3-diol

PubChem CID 91486 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Sphinganine. PubChem CID 91486. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3SPHINGANINE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4SPHINGANINE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=SPHINGANINE