Why the score varies
This ingredient is made commercially by more than one route, and ISO 16128 scores the feedstock actually used. Without a supplier certificate of origin the value cannot be claimed.
| Route | Feedstock | NOI | Share | Notes |
|---|---|---|---|---|
| synthetic | acrylonitrile + 1,4-diaminobutane (petrochemical) | 0.00 | majority, uncertain | |
| natural extraction/fermentation | wheat germ extract or microbial fermentation | 1.00 | minority, uncertain |
How we scored it
Where it comes from
Spermidine is produced either by chemical synthesis from petrochemical acrylonitrile and 1,4-diaminobutane, or by natural extraction, such as from wheat germ, or by fermentation. Both routes are used commercially and the dominant route for cosmetic-grade material could not be confirmed.
In plain English
An antioxidant active naturally found in living cells, used to help condition hair and skin. Depending on the supplier, it may be extracted from natural sources like wheat germ or made synthetically.
CosIng definition: Spermidine is the organic compound that conforms to the formula
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Structure
N'-(3-aminopropyl)butane-1,4-diamine
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2Spermidine. PubChem CID 1102. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
- 3SPERMIDINE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 4SPERMIDINE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=SPERMIDINE