Is sh-Polypeptide-49 natural?

Produced by fermenting genetically modified E. coli expressing a synthetic gene coding for human Fibronectin; the protein is purified from the broth. No alternative commercial route.

A lab-grown protein modeled on human fibronectin that conditions skin. It's made by fermenting bacteria engineered with the human fibronectin gene.

CosIng definition: sh-Polypeptide-49 is a single chain synthetic human peptide, produced by fermentation in E. coli. The starting gene is a synthesized copy of the human gene which codes for Fibronectin used as such or adapted to the production host. It contains a maximum of 2386 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.