Is sh-Polypeptide-47 natural?

Produced by fermenting genetically modified E. coli expressing a synthetic gene coding for human Collagen Alpha 1; the protein is purified from the broth. No alternative route is in commercial use.

A lab-grown protein that mimics human collagen to condition skin. It's made by fermenting bacteria that have been given the human gene for collagen.

CosIng definition: sh-Polypeptide-47 is a single chain synthetic human peptide, produced by fermentation in E. coli. The starting gene is a synthesized copy of the human gene which codes for Collagen Alpha 1 used as such or adapted to the production host. It contains a maximum of 1464 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.