Is sh-Polypeptide-30 natural?

E. coli carrying a synthesised copy of the human Leukemia Inhibitory Factor gene is grown in a fermenter on sugar and ammonium-salt media, then the protein is purified. Other expression hosts would not change the value.

A human signalling protein (leukemia inhibitory factor) produced by E. coli bacteria grown in a fermenter, using a copy of the human gene. It is listed as a skin-conditioning ingredient and is built entirely from the 20 standard amino acids.

CosIng definition: sh-Polypeptide-30 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is synthesized to be identical to the human gene which codes for Leukemia Inhibitory Factor. It contains a maximum of 202 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids