How we scored it
Where it comes from
E. coli carrying a synthesised copy of the human FMS Related Tyrosine Kinase Ligand gene is grown in a fermenter on sugar and ammonium-salt media, then the protein is purified. Other expression hosts would not change the value.
In plain English
A human signalling protein (FMS-related tyrosine kinase ligand) produced by E. coli bacteria grown in a fermenter, using a copy of the human gene. It is listed as a skin-conditioning ingredient and is built entirely from the 20 standard amino acids.
CosIng definition: sh-Polypeptide-26 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is synthesized to be identical to the human gene which codes for FMS Related Tyrosine Kinase Ligand. It contains a maximum of 235 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2SH-POLYPEPTIDE-26. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 3SH-POLYPEPTIDE-26. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=SH-POLYPEPTIDE-26