Is sh-Polypeptide-121 natural?

Produced by fermenting engineered E. coli expressing a synthetic gene coding for human collagen alpha-1(XXI). The protein is assembled entirely from the 20 standard amino acids; no alternative route is used commercially.

A lab-made protein copy of a piece of human collagen, produced by feeding sugar to engineered bacteria that assemble it from amino acids. Used in skincare to form a light film and condition skin.

CosIng definition: sh-Polypeptide-121 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is synthesized to be identical to the human gene which codes for Collagen alpha-1(XXI) chain used such or adapted to the production host. It contains a maximum of 957 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.