How we scored it
17-amino-acid recombinant peptide from standard amino acids via fermentation; no added petrochemical mass.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.
Where it comes from
Produced by fermenting engineered E. coli expressing a gene based on human gamma-endorphin, assembled from standard amino acids. No alternative commercial route.
In plain English
A lab-made peptide modeled on a natural skin-signalling protein, produced by fermenting engineered bacteria. Helps skin hold moisture, feel conditioned, and stay protected.
CosIng definition: sh-Oligopeptide-8 is a single chain recombinant human peptide, produced by fermentation in E. coli and contains 17 amino acids. The starting gene is synthesized to be identical to the human gene which codes for Gamma Endorphin and codes for a total of 267 amino acids which may contain disulfide bonds and/or sugar. The protein consists of the proper sequence of the 20 standard amino acids
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2SH-OLIGOPEPTIDE-8. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 3SH-OLIGOPEPTIDE-8. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=SH-OLIGOPEPTIDE-8