How we scored it
All atoms trace to standard amino acids assembled by E. coli fermentation; no synthetic linkers or caps present → 1.00.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.
Where it comes from
Produced by fermenting genetically modified E. coli expressing the human Insulin-Like Growth Factor gene; purified from the fermentation broth. No petrochemical atoms are introduced.
In plain English
A lab-made copy of human Insulin-Like Growth Factor, produced by fermenting genetically modified bacteria that assemble the protein from ordinary amino acids. Used for skin conditioning.
CosIng definition: It is a single chain recombinant human peptide,produced by fermentation in E. coli. The starting gene is a synthesized copy of the human gene which codes for Insulin-Like Growth Factor used as such or adapted to the production host.
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2SH-OLIGOPEPTIDE-2. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 3SH-OLIGOPEPTIDE-2. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=SH-OLIGOPEPTIDE-2