How we scored it
Where it comes from
E. coli carrying a synthesised copy of the human C-C Motif Chemokine Ligand 5 gene is grown in a fermenter on sugar and ammonium-salt media, then the protein is purified. Other expression hosts would not change the value.
In plain English
A human signalling protein (C-C motif chemokine ligand 5) produced by E. coli bacteria grown in a fermenter, using a copy of the human gene. It is listed as a skin-conditioning ingredient and is built entirely from the 20 standard amino acids.
CosIng definition: sh-Oligopeptide-14 is a single chain recombinant human peptide, produced by fermentation in E. coli. The starting gene is synthesized to be identical to the human gene which codes for C-C Motif Chemokine Ligand 5. It contains a maximum of 91 amino acids which may contain disulfide bonds and/or sugar. The protein consists of the proper sequence of the 20 standard amino acids
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2SH-OLIGOPEPTIDE-14. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 3SH-OLIGOPEPTIDE-14. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=SH-OLIGOPEPTIDE-14