Database/Skin Conditioning/sh-Decapeptide-9
100% natural origin · ISO 16128

Is sh-Decapeptide-9 natural?

Yes. Built entirely from natural amino acids; biotech/chemical coupling reagents leave no mass in the final peptide.

INCI namesh-Decapeptide-9
FunctionSkin Conditioning
FeedstockA biotech-produced peptide identical to a fragment of…

How we scored it

Recombinant/synthesised peptide of 10 natural amino acids (Arg, Gly, Leu, Lys, Phe, Pro, Tyr); peptides built from amino acids are natural-origin regardless of synthesis route.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

A biotech-produced peptide identical to a fragment of human endorphin, assembled from natural amino acids (fermentation/protein-hydrolysate sourced) via recombinant or synthetic coupling. Single route.

In plain English

A lab-made peptide designed to match a natural skin-conditioning protein fragment. Built from the same natural amino acids found in the body.

CosIng definition: sh-Decapeptide-9 is a recombinant human peptide produced synthetically to be identical to the protein, Endorphin. It contains 10 amino acids consisting of arginine, glycine, leucine, lysine, phenylalanine, proline and tyrosine

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2SH-DECAPEPTIDE-9. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  3. 3SH-DECAPEPTIDE-9. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=SH-DECAPEPTIDE-9