Database/Fragrance/Sclareolide
100% natural origin · ISO 16128

Is Sclareolide natural?

Yes. Sclareolide retains the full carbon skeleton of sclareol, a diterpene extracted from clary sage; oxidative reagents add no atoms.

INCI nameSclareolide
CAS564-20-5
FormulaC16H26O2 · 250.38 Da
FunctionFragrance · Skin Conditioning
FeedstockProduced by microbial or chemical oxidative degradation of…

How we scored it

Decalin-lactone skeleton is the intact carbon framework of natural sclareol; oxidative cleavage reagents leave no mass = 1.0
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Produced by microbial or chemical oxidative degradation of sclareol, a diterpene extracted from clary sage (Salvia sclarea) concrete. No commercially significant total-synthesis route exists.

In plain English

A fragrance ingredient with a woody, ambery scent, made by processing sclareol, a natural compound extracted from clary sage plants.

Structure

2D structure of Sclareolide

(3aR,5aS,9aS,9bR)-3a,6,6,9a-tetramethyl-1,4,5,5a,7,8,9,9b-octahydrobenzo[e][1]benzofuran-2-one

PubChem CID 929262 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Sclareolide. PubChem CID 929262. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3SCLAREOLIDE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4SCLAREOLIDE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=SCLAREOLIDE