Database/Antioxidant/Pyrroloquinoline Quinone
100% natural origin · ISO 16128

Is Pyrroloquinoline Quinone natural?

Yes. PQQ is predominantly produced by microbial fermentation, the same production class as adenosine and coenzyme Q10.

INCI namePyrroloquinoline Quinone
CAS72909-34-3
FormulaC14H6N2O8 · 330.21 Da
FunctionAntioxidant · Humectant
FeedstockPyrroloquinoline Quinone is produced commercially by bacterial fermentation,…

How we scored it

Redox cofactor commercially produced by bacterial fermentation, consistent with this site's fermentation-product examples → 1.0
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Pyrroloquinoline Quinone is produced commercially by bacterial fermentation, similar to other fermentation-derived cosmetic actives such as coenzyme Q10. A minor chemical-synthesis route also exists, so market-share confidence is limited.

In plain English

An antioxidant active that helps protect and condition skin. It is produced by fermenting bacteria, similar to how some vitamins and coenzymes are made.

CosIng definition: Pyrroloquinoline Quinone is the organic compound that conforms to the formula:

Structure

2D structure of Pyrroloquinoline Quinone

4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid

PubChem CID 1024 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Pyrroloquinoline Quinone. PubChem CID 1024. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3PYRROLOQUINOLINE QUINONE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4PYRROLOQUINOLINE QUINONE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=PYRROLOQUINOLINE%20QUINONE