Database/Antistatic/Pyridoxine
100% petroleum · ISO 16128

Is Pyridoxine natural?

No. Like niacinamide, industrial pyridoxine is a fully synthetic pyridine derivative; no commercially significant natural or fermentation route exists.

INCI namePyridoxine
CAS65-23-6
FormulaC8H11NO3 · 169.18 Da
FunctionAntistatic · Hair Conditioning
FeedstockManufactured by fully synthetic chemical routes from petrochemical…

How we scored it

Pyridine-ring vitamin; commercial Vitamin B6 is made by full chemical synthesis (oxazole/Perkin-type routes), no significant fermentation supply. 0/169.18 = 0.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Manufactured by fully synthetic chemical routes from petrochemical intermediates, such as oxazole condensation, unlike some other B-vitamins. No significant fermentation-based supply exists for cosmetic-grade pyridoxine.

In plain English

Vitamin B6, added to condition skin and hair and reduce static. Although it is chemically a vitamin, the form used in cosmetics is manufactured by full chemical synthesis, not fermentation.

Natural alternatives with the same function

Acronychia Acidula Fruit Extract 100% natural origin

An extract of lemon aspen, an Australian native fruit, used to condition skin and hair and help hold…

 Alanine 100% natural origin

An amino acid used for skin and hair conditioning, part of skin's natural moisturising factor. Made by fermenting…

 Arginine 100% natural origin

An amino acid found in skin and hair proteins, used for conditioning and moisture-binding. Made by fermenting plant…

 Asparagine 100% natural origin

An amino acid made by fermenting plant sugars, similar to other food-fermentation processes. Helps condition hair and skin…

 Aspartic Acid 100% natural origin

An amino acid used for skin conditioning and moisture retention. Usually produced by fermentation or by an enzyme…

 Capryloyl Hydrolyzed Collagen 100% natural origin

Collagen broken into small protein fragments and attached to caprylic acid, an eight-carbon fatty acid from coconut or…

Structure

2D structure of Pyridoxine

4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol

PubChem CID 1054 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Pyridoxine. PubChem CID 1054. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3PYRIDOXINE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4PYRIDOXINE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=PYRIDOXINE