Database/Skin Conditioning/Polypeptide-23
100% natural origin · ISO 16128

Is Polypeptide-23 natural?

Yes. Assembled entirely from amino acids, which are fermentation or protein-hydrolysate feedstocks; synthesis chemistry adds no retained mass.

INCI namePolypeptide-23
FunctionSkin Conditioning
FeedstockA 153-amino-acid peptide assembled from standard amino acids,…

How we scored it

153-residue peptide; amino-acid building blocks are fermentation/hydrolysate-derived, coupling chemistry adds no retained mass -> 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

A 153-amino-acid peptide assembled from standard amino acids, which are fermentation or protein-hydrolysate derived. CosIng labels the assembly 'synthetic', but no non-amino-acid mass is retained in the final product.

In plain English

A large, lab-assembled peptide built from amino acids, used to help condition and support the look of skin. It functions like a small protein fragment.

CosIng definition: Polypeptide-23 is a synthetic peptide containing 153 amino acids consisting of alanine, arginine, asparagine, aspartic acid, cysteine, glutamine, glutamic acid, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, proline, serine, threonine, tryptophan, tyrosine and valine

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2POLYPEPTIDE-23. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  3. 3POLYPEPTIDE-23. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=POLYPEPTIDE-23