Database/Skin Conditioning/Piperine
100% natural origin · ISO 16128

Is Piperine natural?

Yes. Extracted and purified directly from black pepper fruit, a natural-origin feedstock; extraction is the standard commercial route.

INCI namePiperine
CAS94-62-2
FormulaC17H19NO3 · 285.34 Da
FunctionSkin Conditioning
FeedstockExtracted from black pepper (Piper nigrum) fruit. Total…

How we scored it

Piperidine alkaloid; commercially extracted from black pepper fruit (5-9% content makes extraction economical) rather than synthesised, so it counts as natural.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Extracted from black pepper (Piper nigrum) fruit. Total synthesis is known but is not the commercial cosmetic-ingredient route.

In plain English

The compound that gives black pepper its bite, used here as a skin-conditioning ingredient. It's extracted directly from pepper fruit.

CosIng definition: Piperine is the organic compound that conforms to the formula

Structure

2D structure of Piperine

(2E,4E)-5-(1,3-benzodioxol-5-yl)-1-piperidin-1-ylpenta-2,4-dien-1-one

PubChem CID 638024 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Piperine. PubChem CID 638024. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3PIPERINE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4PIPERINE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=PIPERINE