Database/Emulsion Stabilising/Phosphatidylserine
100% natural origin · ISO 16128

Is Phosphatidylserine natural?

Yes. Every fragment, the glycerin backbone, two fatty acids, phosphate and the amino acid serine, is natural-origin; esterification adds no petrochemical mass.

INCI namePhosphatidylserine
CAS1446756-47-3
FormulaC42H82NO10P · 792.1 Da
FunctionEmulsion Stabilising · Hair Conditioning
FeedstockPhosphatidylserine is a phospholipid built from glycerin, two…

How we scored it

Glycerol (natural) + 2 fatty acyl chains (natural, oleochemical) + phosphate (mineral) + serine (natural amino acid), assembled by esterification. 792/792 = 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Phosphatidylserine is a phospholipid built from glycerin, two natural fatty acids, mineral phosphate and the amino acid serine, typically derived from soy or sunflower lecithin. No petrochemical route is used commercially.

In plain English

A natural fat-based ingredient that helps condition skin and hair and stabilise emulsions. It is built from glycerin, plant or animal fatty acids and phosphate, similar to phospholipids found in cell membranes.

CosIng definition: Fatty acid diglycerides, phosphate monoesters, 2-amino-2-carboxyethyl ester

Structure

2D structure of Phosphatidylserine

(2S)-2-amino-3-[[(2R)-2,3-di(octadecanoyloxy)propoxy]-hydroxyphosphoryl]oxypropanoic acid

PubChem CID 9547096 ↗

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2Phosphatidylserine. PubChem CID 9547096. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
  3. 3PHOSPHATIDYLSERINE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  4. 4PHOSPHATIDYLSERINE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=PHOSPHATIDYLSERINE