Database/Skin Conditioning/Pentapeptide-34
100% natural origin · ISO 16128

Is Pentapeptide-34 natural?

Yes. Built entirely from natural/fermentation-derived amino acids; synthesis reagents leave no mass in the final peptide.

INCI namePentapeptide-34
FunctionSkin Conditioning
FeedstockChemically synthesised (solid-phase) from the amino acids alanine,…

How we scored it

Peptide of alanine, glycine, leucine, valine; amino-acid peptides are 1.0 regardless of solid-phase synthesis route.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Chemically synthesised (solid-phase) from the amino acids alanine, glycine, leucine and valine, which are themselves fermentation or protein-hydrolysate products. The coupling chemistry leaves no mass in the finished peptide.

In plain English

A lab-assembled chain of five natural amino acids (also found in proteins) used in anti-ageing skincare to support skin conditioning. Built from the same building blocks the body uses to make proteins.

CosIng definition: Pentapeptide-34 is the synthetic peptide consisting of alanine, glycine, leucine and valine.

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2PENTAPEPTIDE-34. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  3. 3PENTAPEPTIDE-34. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=PENTAPEPTIDE-34