Database/Hair Conditioning/Pentapeptide-20
100% natural origin · ISO 16128

Is Pentapeptide-20 natural?

Yes. Every residue is a proteinogenic amino acid from fermentation or protein hydrolysis, and the INCI name shows no petrochemical acyl cap.

INCI namePentapeptide-20
FunctionHair Conditioning
FeedstockDominant route: chemical peptide synthesis from fermentation-derived L-amino…

How we scored it

Five-residue peptide of proteinogenic amino acids (Gly, Ile, Pro, Ser); no acetyl or lipid cap is named; peptides = 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.

Where it comes from

Dominant route: chemical peptide synthesis from fermentation-derived L-amino acids; protecting groups and coupling agents leave no mass. No alternative route is commercially significant.

In plain English

A short peptide of five amino acids (glycine, isoleucine, proline and serine) used to condition hair. It is assembled from amino acids that are made by fermentation or protein hydrolysis.

CosIng definition: Pentapeptide-20 is a synthetic peptide consisting of glycine, isoleucine, proline, and serine

References

  1. 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
  2. 2PENTAPEPTIDE-20. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
  3. 3PENTAPEPTIDE-20. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=PENTAPEPTIDE-20