How we scored it
Single sesquiterpene lactone, commercially extracted intact from feverfew; no synthetic fragment to split.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.
Where it comes from
Isolated by extraction from feverfew leaf and flower, its natural source. Chemical synthesis exists but is not the typical cosmetic-grade supply route.
In plain English
A natural compound extracted from feverfew plant, used in skincare for its skin-conditioning properties.
CosIng definition: Parthenolide is the organic compound that conforms to the formula
Structure
(1S,2S,4R,7E,11S)-4,8-dimethyl-12-methylidene-3,14-dioxatricyclo[9.3.0.02,4]tetradec-7-en-13-one
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2Parthenolide. PubChem CID 6473881. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
- 3PARTHENOLIDE. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 4PARTHENOLIDE. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=PARTHENOLIDE