How we scored it
Amide of palmitic acid (oleochemical, natural) + Tripeptide-5 (natural amino acids) → total/total = 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.
Where it comes from
Made by attaching palmitic acid, a natural fatty acid, to a three-amino-acid peptide chain via an amide bond. Both building blocks are natural origin.
In plain English
A peptide ingredient used in anti-ageing skincare to support the skin's collagen network. It is made by attaching palmitic acid, a natural fatty acid, to a chain of three amino acids.
CosIng definition: Palmitoyl Tripeptide-5 is the reaction product of palmitic acid and Tripeptide-5
Structure
(2S)-6-amino-2-[[(2S)-2-[[(2S)-6-amino-2-(hexadecanoylamino)hexanoyl]amino]-3-methylbutanoyl]amino]hexanoic acid
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2Palmitoyl Tripeptide-5. PubChem CID 11950477. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
- 3PALMITOYL TRIPEPTIDE-5. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 4PALMITOYL TRIPEPTIDE-5. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=PALMITOYL%20TRIPEPTIDE-5