How we scored it
Palmitic acid (natural, oleochemical) + tripeptide-38 (natural, fermentation amino acids) joined by amide bond, condensation water not counted. Whole molecule = 1.0.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.
Where it comes from
Made by condensing palm/coconut-derived palmitic acid with a synthetically-assembled tripeptide built from fermentation-derived amino acids. Coupling reagents leave no mass in the final product.
In plain English
A skin-conditioning peptide ingredient made by attaching palm or coconut-derived palmitic acid to a chain of three amino acids. It is manufactured by chemically joining these natural building blocks.
CosIng definition: Palmitoyl Tripeptide-38 is the reaction product of palmitic acid and Tripeptide-38
Structure
(2S)-6-amino-2-[[(2S)-2-[[(2S)-6-amino-2-(hexadecanoylamino)hexanoyl]amino]-4-methylsulfonylbutanoyl]amino]hexanoic acid
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2Palmitoyl Tripeptide-38. PubChem CID 71587932. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
- 3PALMITOYL TRIPEPTIDE-38. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 4PALMITOYL TRIPEPTIDE-38. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=PALMITOYL%20TRIPEPTIDE-38