How we scored it
C37H65N7O5, 688 Da = palmitoyl C16H31O 239 + Arg-Phe-Lys 449 (formula matches Pal-Arg-Phe-Lys-OH). No petrochemical cap: 688 / 688 = 1.00.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.
Where it comes from
Palmitic acid from palm or coconut oil is coupled to a tripeptide of fermentation-derived amino acids by peptide synthesis. No alternative route changes the value.
In plain English
A fatty-acid-linked peptide: palmitic acid (from palm or coconut oil) joined to a chain of three amino acids (arginine, phenylalanine, lysine). It is used as a skin-conditioning ingredient. The amino acids come from fermentation and are assembled in a factory.
CosIng definition: Palmitoyl Tripeptide-28 is the reaction product of palmitic acid and Tripeptide-28
Structure
(2S)-6-amino-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-(hexadecanoylamino)pentanoyl]amino]-3-phenylpropanoyl]amino]hexanoic acid
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2Palmitoyl Tripeptide-28. PubChem CID 171390254. National Center for Biotechnology Information. pubchem.ncbi.nlm.nih.gov ↗
- 3PALMITOYL TRIPEPTIDE-28. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 4PALMITOYL TRIPEPTIDE-28. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=PALMITOYL%20TRIPEPTIDE-28