How we scored it
Palmitoyl C16H31O from palmitic acid (natural) amide-bonded to a tetrapeptide of amino acids (natural); acid chloride Cl and coupling reagents leave no mass; 1.0. Sequence not verified.
What counts. ISO 16128-2 scores the atoms that remain in the final ingredient. Reagents, solvents, catalysts and protecting groups used during manufacture leave no mass behind and are not counted.
Where it comes from
Palmitic acid is converted to its chloride and coupled to a tetrapeptide assembled from fermentation-derived amino acids. Only standard amino acids were assumed, as the sequence was not checked.
In plain English
A short chain of four amino acids joined to palmitic acid, a fatty acid that makes it more oil-soluble, used to condition skin. It is made in the laboratory from amino acids and palmitic acid, which originate from fermentation, protein hydrolysis and palm or coconut oil.
CosIng definition: Palmitoyl Tetrapeptide-12 is the product obtained by the reaction of palmitic acid chloride and Tetrapeptide-12
References
- 1ISO 16128-1:2016 and ISO 16128-2:2017 — Guidelines on technical definitions and criteria for natural and organic cosmetic ingredients and products. ISO, Geneva.
- 2PALMITOYL TETRAPEPTIDE-12. CosIng — European Commission cosmetic ingredient database. ec.europa.eu/cosing ↗
- 3PALMITOYL TETRAPEPTIDE-12. CosIng u2014 European Commission database for information on cosmetic substances and ingredients. https://ec.europa.eu/growth/tools-databases/cosing/search?search=PALMITOYL%20TETRAPEPTIDE-12